Ok guys here we go..
Using JD jetting I went with blue needle 2nd notch from top.
172 main jet
52 pilot jet (it had a 42 and I don't know if shop had changed that or it was factory but without the power pump 42 worked just fine)
The R&D power pump had a stronger spring to change out but for the life of me I could not get it to work. The plastic shaft that the spring sits on is shorter than the new spring so the last loop of the spring wants to sit under the plastic shaft, it may be possible to use the spring if you have 2 people helping to keep the spring compressed as its installed. Luckily the Jd jet kit comes with an o-ring that works in a way that makes the stock spring stronger so after a lot of frustration I went with the stock spring.
I also installed a fuel mix screw that sits just below the bottom of the carb and I have the mix screw 2 turns out. I also have the power pump 2 turns out. It runs pretty damn good but I think I could even get it finer tuned but its so close I probably won't bother.
I also got the throttle reduce spring from
http://www.tokyomods.com/honda/99-06%20CRF250%20RX.html
I had to modify the spring a little, on the spring there is a short end and a longer end. I clipped the longer end off and re bent it to the same shape. If you do the same mod just try to get it close as you can to the stock spring and it has a much better fit.
I used a fish scale to measure the pull and I'm sure the accuracy is going to be way off but you can still see the results.
Stock pull was right at 2lbs and after modified it was 1lbs. I have not taken it out on a ride other than just up my street to test the jetting so I'm not sure if after a long ride if there will still be thumb strain but I would bet that even if the scale was not accurate it did have half the pull and it did not seem to soft as the carb still worked like it should.
products rated
JD Jet kit 10/10
power pump (no rating because I'm on the fence if this did anything)
thumb spring 7/10 (spring needed modified)
Hope this helps you decide what will work best for you,
-Voodoo